University Interdisciplinary Programs

Integrative Sciences Initiative and Building

The Integrative Sciences Initiative will change the way we do science at NC State by facilitating new and impactful synergies in interdisciplinary research and education.

Transforming the Sciences

The Integrative Sciences Initiative (ISI) tackles challenges posed by infectious diseases and cancer, and efforts will continue to elevate NC State’s reputation as an outstanding land-grant R1 university. To meet these challenges, three thematic areas have been identified to collaboratively study, synthesize, and screen molecules and molecular pathways in the context of human and animal disease. Those are: molecular mechanisms of metabolism and disease; molecular synthesis and characterization; and molecular therapeutics and drug discovery.

Interdisciplinary research and teaching across these themes will embrace cutting edge technologies in shared spaces and core facilities provided by the ISI. Synergy within and across themes will infuse the training and research environment for undergraduate and graduate students, faculty and staff, in a manner that is unprecedented at NC State.

The new $160 million Integrative Sciences Building (ISB) — the heart of the ISI — will be built in the location of the former Harrelson Hall. The new facility will provide much-needed STEM (science, technology, engineering and mathematics) teaching and research space on north campus, and serve as a catalyst for transforming the sciences at NC State. It will be an inspiring, flexible model for academic and research creativity that is focused on collaboration, discovery and transfer of knowledge.

Integrative Sciences Building

Heart of Campus

The ISB will be located on the former Harrelson Hall site adjacent to the Brickyard.

153,000 GSF

The building will include a mix of teaching, research, collaboration, amenity and support space.

$160 Million Investment

$80 million of the project cost will be provided by the state and $80 million will be funded by the university.

The Need for a New Kind of Space

NC State has outgrown our existing spaces for lab-based science programs, such as chemistry, biochemistry and biological sciences, which are critical on a campus where more than half of our graduates major in STEM fields. In order to maintain our presence as one of the most elite STEM universities in the nation and to continue attracting the best and brightest faculty and students, we must have top-notch basic and applied molecular science programs and facilities.

The Integrative Sciences Building will create a community of interdisciplinary scholars focused on tackling societal grand challenges in human and non-human animal health and the environment. Research and teaching will embrace cutting edge technologies in shared spaces and core facilities. Synergy within and across disciplines will infuse the training and research environment for undergraduate and graduate students, faculty and staff, in a manner that is unprecedented at NC State.

Disciplines represented in the Integrated Sciences Building will be STEM focused. Education and training programs will focus on team science, inquiry-driven coursework across disciplines, communication and leadership, diversity and preparing for the jobs of tomorrow. Research themes will include molecular synthesis and characterization, molecular mechanisms of metabolism and disease, and molecular therapeutics and drug discovery.

Project Milestones

In January 2021, NC State University engaged Moseley Architects and ZGF Architects along with a team of consultants to complete advanced planning for the Integrative Sciences Building, which was wrapped up in August 2021. Tentative milestones for the project moving forward include:

  • Design development by June 2022;
  • Construction documents by December 2022;
  • Construction begins in summer 2023 and
  • Construction completed in spring 2026.