Matthew Foley

Bio

My long-term interests are the use interdisciplinary approaches to define the underlying mechanisms of microbiome-associated diseases to create novel therapeutics. My graduate training at the University of Michigan introduced me to the gut microbiome and bacterial carbohydrate metabolism, which lead to and interest in how bacterial metabolites shape the gut environment. My postdoctoral training in the Theriot Lab at NC State University focused on bacterial bile acid metabolism and its regulation of C. difficile pathogenesis. Currently, I works alongside academics in the Barrangou Lab at NCSU and industry scientists at Ancilia Biosciences in NYC to help engineer enhanced bacterial therapeutics with CRISPR-Cas to overcome the barriers that bacteriophage pose to bacterial therapeutic efficacy.