By 2050, it is projected that antimicrobial resistant pathogens will result in the death of 10 million people worldwide \u2013 even more than cancer (8.2 million). The problem is greatly exacerbated by the lack of new antimicrobials to treat these infections, gaps in data exchange, changing climate, the need for rapid diagnostics, and researchers working in silos. NC State has the expertise to overcome these challenges and improve outcomes by targeting AMR at the local, national, and global levels using the One Health lens.<\/p>\n\n\n\n
The Grand Challenges Addressing Program on Antimicrobial Resistance (GCAP-AMR) will catalyze NC State\u2019s tremendous strengths in areas ranging from molecules to population-based approaches, centered around themes including:<\/p>\n\n\n\n
The network figure below illustrates the diverse faculty at NC State with published research related to AMR. As of fall 2024, faculty members from seven colleges belong to this research network: College of Agriculture & Life Sciences (CALS), College of Veterinary Medicine (CVM), College of Sciences (COS), College of Engineering (COE), Wilson College of Textiles (WCOT), College of Natural Resources (CNR), and College of Humanities & Social Sciences (CHASS). Each node (dot) represents an individual faculty member and each edge (line between the dots) represents a co-authored AMR publication, with the edge width proportional to the number of publications.<\/p>\n\n\n\n
Nearly 300 faculty belong to this NC State AMR research network, but many of these faculty are working in disciplinary (within-college) silos, and many more are not yet collaborating with other NC State faculty on this research at all. GCAP-AMR aims to change that by incentivizing new interdisciplinary research directions through seed grants and providing opportunities to bring faculty on the outskirts of this figure more firmly into the collaborative network. Harnessing NC State\u2019s full range of AMR expertise will drive innovative One Health solutions.<\/p>\n\n\n\n
The Global One Health Academy offered seed grants in Fall 2024 to accelerate interdisciplinary AMR research grounded in the One Health framework. Two funding types were available: Launch Projects of up to $50,000 to support more advanced-stage projects likely to lead to external grant submission within a short time window, and Pilot Projects of up to $15,000 to support more nascent collaborations and\/or new research directions. Five projects were funded through this seed grant call.<\/p>\n\n\n\n